rotundifolioside H

Term ID

CHEBI:66315

Synonyms

(3beta,16alpha)-16,23-dihydroxy-13,28-epoxyurs-11-en-3-yl beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->2)-6-deoxy-beta-D-galactopyranoside
13beta,28-epoxy-16alpha,23-dihydroxyurs-11-en-3beta-yl beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->2)-beta-D-fucopyranoside

Definition

A triterpenoid saponin that consists of urs-11-ene substituted by an epoxy group across positions 13 and 28, a hydroxy groups at position 16 and 23 and a beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->2)-beta-D-fucopyranosyloxy group at position 3 (the 3beta,16alpha stereoisomer). Isolated from the fruits of Bupleurum rotundifolium, it exhibits antiproliferative activity against cancer cells.

References

PMID:12672986

Ontology

ChEBI ( EBI )

Relationships

is a type of: bridged compound cyclic ether hexacyclic triterpenoid trisaccharide derivative triterpenoid saponin

bridged compound cyclic ether hexacyclic triterpenoid trisaccharide derivative triterpenoid saponin Show first 5 Terms
has_parent_hydride: ursane

ursane Show first 5 Terms
has_role: antineoplastic agent plant metabolite

antineoplastic agent plant metabolite Show first 5 Terms

Phenotype

Phenotype resulting from rotundifolioside H

Phenotype where environments contain rotundifolioside H

Phenotype modified by environments containing rotundifolioside H

Human Disease / Model Data

Citations