hookerianamide K

Term ID

CHEBI:66023

Synonyms

(20S)-20-(N-dimethylamino)-3beta-(N-dimethylamino)-pregn-4,14-diene
(3beta,20S)-N(3),N(3),N(20),N(20)-tetramethylpregna-4,14-diene-3,20-diamine

Definition

A steroid alkaloid that is pregn-4,14-diene substituted by N-dimethylamino groups at positions 3 and 20 (the 3beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.

References

PMID:18681480
Reaxys:18885919

Ontology

ChEBI ( EBI )

Relationships

is a type of: steroid alkaloid tertiary amino compound

steroid alkaloid tertiary amino compound Show first 5 Terms
has_parent_hydride: pregnane

pregnane Show first 5 Terms
has_role: antibacterial agent antileishmanial agent EC 3.1.1.8 (cholinesterase) inhibitor metabolite

antibacterial agent antileishmanial agent EC 3.1.1.8 (cholinesterase) inhibitor metabolite Show first 5 Terms

Phenotype

Phenotype resulting from hookerianamide K

Phenotype where environments contain hookerianamide K

Phenotype modified by environments containing hookerianamide K

Human Disease / Model Data

Citations