Search Ontology:
ChEBI
calotropone
- Term ID
- CHEBI:65568
- Synonyms
-
- (3beta,12beta,14beta,17alpha)-3,14,17-trihydroxy-20-oxopregn-5-en-12-yl benzoate
- 12beta-benzoyloxy-3beta,14beta,17beta-trihydroxypregnane-20-one
- 12beta-O-benzoyl-3beta,14beta,17beta-trihydroxypregnane-20-one
- 3beta,14beta,17-trihydroxy-20-oxo-17alpha-pregn-5-en-12beta-yl benzoate
- Definition
- A 20-oxo steroid that is 17alpha-pregn-5-en-20-one substituted by a benzoyloxy group at position 12 and hydroxy groups at positions 3, 14 and 17 (the 3beta,12beta,14beta stereoisomer). It is isolated from the roots of Calotropis gigantea and displays inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.
- References
-
- PMID:19052526
- Reaxys:18872733
- Ontology
- ChEBI ( EBI )
- is a type of
- has_parent_hydride
-
- has_role
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from calotropone
Phenotype where environments contain calotropone
Phenotype modified by environments containing calotropone
Human Disease / Model Data
Citations