aspergillide A

Term ID

CHEBI:65450

Synonyms

(1R,5S,9E,11R,14S)-14-hydroxy-5-methyl-4,15-dioxabicyclo[9.3.1]pentadec-9-en-3-one

Definition

A macrolide that is 4,15-dioxabicyclo[9.3.1]pentadec-9-en-3-one substituted by a hydroxy group at position 14 and a methyl group at position 5 (the 1R,5S,9E,11R,14S stereoisomer). It is isolated from the marine-derived fungus Aspergillus ostianus and exhibits cytotoxic activity against mouse lymphocytic leukemia cells (L1210).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: bridged compound cyclic ether macrolide secondary alcohol

bridged compound cyclic ether macrolide secondary alcohol Show first 5 Terms
has_role: antineoplastic agent Aspergillus metabolite

antineoplastic agent Aspergillus metabolite Show first 5 Terms

Phenotype

Phenotype resulting from aspergillide A

Phenotype where environments contain aspergillide A

Phenotype modified by environments containing aspergillide A

Human Disease / Model Data

Citations