Search Ontology:
ChEBI

pregabalin

Term ID
CHEBI:64356
Synonyms
  • (3S)-3-(aminomethyl)-5-methylhexanoic acid
  • (S)-3-Isobutyl GABA
  • 3-Isobutyl GABA
  • Lyrica
  • pregabalin
Definition
A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from pregabalin
Phenotype where environments contain pregabalin
Phenotype modified by environments containing pregabalin
Human Disease / Model Data
Citations
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