(2R,3S)-EHNA hydrochloride

Term ID

CHEBI:64139

Synonyms

(2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol hydrochloride
(2R,3S)-3-(adenin-9-yl)-2-nonanol hydrochloride
(2R,3S)-9-(2-hydroxy-3-nonyl)adenine hydrochloride
(2R,3S)-EHNA.HCl
(R,S)-6-amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol hydrochloride
erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride

Definition

A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase.

References

Reaxys:4729841

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride

hydrochloride Show first 5 Terms
has_part: (2R,3S)-EHNA(1+)

(2R,3S)-EHNA(1+) Show first 5 Terms
has_role: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor EC 3.5.4.4 (adenosine deaminase) inhibitor

EC 3.1.4.* (phosphoric diester hydrolase) inhibitor EC 3.5.4.4 (adenosine deaminase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from (2R,3S)-EHNA hydrochloride

Phenotype where environments contain (2R,3S)-EHNA hydrochloride

Phenotype modified by environments containing (2R,3S)-EHNA hydrochloride

Human Disease / Model Data

Citations