1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

Term ID

CHEBI:64091

Synonyms

1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazinediium dichloride
GBR 12935 dihydrochloride

Definition

A hydrochloride salt that is obtained by reaction of 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine with two equivalents of hydrogen chloride. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride

hydrochloride Show first 5 Terms
has_part: 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+)

1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazinediium(2+) Show first 5 Terms
has_role: dopamine uptake inhibitor

dopamine uptake inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

Phenotype where environments contain 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

Phenotype modified by environments containing 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

Human Disease / Model Data

Citations