amorolfine hydrochloride

Term ID

CHEBI:59649

Synonyms

(2R,6S)-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine hydrochloride
meso-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine

Definition

A hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used for the topical treatment of fungal nail and skin infections.

References

Beilstein:9364702
CAS:78613-38-4
KEGG:D01720

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride morpholine antifungal drug

hydrochloride morpholine antifungal drug Show first 5 Terms
has_part: amorolfine(1+)

amorolfine(1+) Show first 5 Terms
has_role: EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor EC 1.14.13.132 (squalene monooxygenase) inhibitor EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor

EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor EC 1.14.13.132 (squalene monooxygenase) inhibitor EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from amorolfine hydrochloride

Phenotype where environments contain amorolfine hydrochloride

Phenotype modified by environments containing amorolfine hydrochloride

Human Disease / Model Data

Citations