clodronic acid disodium salt

Term ID

CHEBI:59586

Synonyms

clodronate disodium
clodronate sodium
clodronic acid disodium salt
disodium (dichloromethanediyl)bis[hydrogen (phosphonate)]
disodium (dichloromethylene)bisphosphonate
disodium (dichloromethylene)diphosphonate
disodium clodronate
disodium dichloromethylene diphosphonate
disodium dihydrogen (dichloromethylene)diphosphonate
sodium clodronate

Definition

The disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.

References

Beilstein:5841154
CAS:22560-50-5
KEGG:D07720

Ontology

ChEBI ( EBI )

Relationships

is a type of: one-carbon compound organic sodium salt

one-carbon compound organic sodium salt Show first 5 Terms
has_part: clondronate(2-)

clondronate(2-) Show first 5 Terms
has_role: bone density conservation agent

bone density conservation agent Show first 5 Terms
inverse has_part: disodium clodronate tetrahydrate

disodium clodronate tetrahydrate Show first 5 Terms

Phenotype

Phenotype resulting from clodronic acid disodium salt

Phenotype where environments contain clodronic acid disodium salt

Phenotype modified by environments containing clodronic acid disodium salt

Human Disease / Model Data

Citations