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ChEBI

emivirine

Term ID
CHEBI:44143
Synonyms
  • 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)pyrimidine-2,4(1H,3H)-dione
  • 6-benzyl-1-(ethoxymethyl)-5-(1-methylethyl)uracil
  • 6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 6-BENZYL-1-ETHOXYMETHYL-5-ISOPROPYL URACIL
  • Coactinon
  • emivirine
  • MKC-442
Definition
A pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatment of HIV.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from emivirine
Phenotype where environments contain emivirine
Phenotype modified by environments containing emivirine
Human Disease / Model Data
Citations