(3R,5S)-fluvastatin

Term ID

CHEBI:38565

Synonyms

(+)-(3R,5S)-fluvastatin
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

Definition

A (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid diastereoisomer in which the stereocentres beta- and delta- to the carboxy group have R and S configuration, respectively. The drug fluvastatin is an equimolar mixture of this compound and its enantiomer.

References

Beilstein:8169392
PMID:11817313
PMID:12489926
PMID:12891229
PMID:16480934
Reaxys:8169392

Ontology

ChEBI ( EBI )

Relationships

is a type of: (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid statin (synthetic)

(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid statin (synthetic) Show first 5 Terms
inverse has_part: fluvastatin

fluvastatin Show first 5 Terms
inverse is_conjugate_base_of: (3R,5S)-fluvastatin(1-)

(3R,5S)-fluvastatin(1-) Show first 5 Terms
inverse is_enantiomer_of: (3S,5R)-fluvastatin

(3S,5R)-fluvastatin Show first 5 Terms
is_conjugate_acid_of: (3R,5S)-fluvastatin(1-)

(3R,5S)-fluvastatin(1-) Show first 5 Terms
is_enantiomer_of: (3S,5R)-fluvastatin

(3S,5R)-fluvastatin Show first 5 Terms

Phenotype

Phenotype resulting from (3R,5S)-fluvastatin

Phenotype where environments contain (3R,5S)-fluvastatin

Phenotype modified by environments containing (3R,5S)-fluvastatin

Human Disease / Model Data

Citations