3-methyl-2-oxovaleric acid

Term ID

CHEBI:35932

Synonyms

• 2-Oxo-3-methyl-n-valeric acid
• 2-Oxo-3-methylpentanoic acid
• 2-Oxo-3-methylvalerate
• 2-Oxo-3-methylvaleric acid
• 2-Oxoisoleucine
• 2-oxokolavenic acid
• 3-ethyl-3-methylpyruvic acid
• 3-methyl-2-oxopentanoic acid
• 3-methyl-2-oxovaleric acid
• alpha-keto-beta-methyl-n-valeric acid
• alpha-keto-beta-methylvaleric acid
• alpha-oxo-beta-methyl-n-valeric acid
• alpha-oxo-beta-methylvaleric acid
• ketoisoleucine

Definition

A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).

References

• Beilstein:1098987
• CAS:1460-34-0
• Gmelin:971983
• HMDB:HMDB0000491
• KEGG:C03465
• PMID:1638756
• PMID:17190852
• PMID:759179
• Reaxys:1098987

Ontology

ChEBI  ( EBI )

Resources

CTD