cephalexin

Term ID

CHEBI:3534

Synonyms

• (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
• 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
• 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid
• Cefalexin
• cefalexina
• cefalexine
• cefalexinum
• Celexin
• Cepastar
• Cepexin
• Cephacillin
• Ceporexin
• CEX

Definition

A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.

References

• Beilstein:965503
• CAS:15686-71-2
• DrugBank:DB00567
• Drug_Central:571
• HMDB:HMDB0014707
• KEGG:C06895
• KEGG:D00263
• LINCS:LSM-5957
• PMID:10930630
• PMID:12569987
• PMID:12833570
• PMID:1384868
• PMID:2083978
• PMID:22559990
• PMID:23061564
• PMID:23457080
• PMID:23545436
• PMID:23688276
• PMID:23811740
• PMID:24268227
• PMID:24548092
• PMID:29017833
• Patent:US3275626
• Patent:US3507861
• Reaxys:4238892
• VSDB:1791
• Wikipedia:Cefalexin

Ontology

ChEBI  ( EBI )

Resources

CTD