Search Ontology:
ChEBI
candoxatril
- Term ID
- CHEBI:3353
- Synonyms
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- 4-({1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid
- [4(S)-cis]-4-[[[1-[3-[(2,3-dihydro-1H-indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid
- candoxatril
- cis-4-{[(1-{(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl}cyclopentyl)carbonyl]amino}cyclohexanecarboxylic acid
- Definition
- The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart failure.
- References
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- Beilstein:8374063
- CAS:123122-55-4
- DrugBank:DB00616
- KEGG:D01070
- Patent:EP274234
- Patent:US5030654
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_functional_parent
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from candoxatril
Phenotype where environments contain candoxatril
Phenotype modified by environments containing candoxatril
Human Disease / Model Data
Citations