Search Ontology:
ChEBI
tolvaptan
- Term ID
- CHEBI:32246
- Synonyms
-
- jinarc
- N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
- OPC 41061
- OPC-41061
- samsca
- Tolvaptan
- Definition
- A benzazepine derivative incorporating a benzenedicarboxamide function whch is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency. Tolvaptan is a racemate consisting of a 1:1 mixture of 5R and 5S stereomers.
- References
-
- CAS:150683-30-0
- Drug_Central:4110
- KEGG:C12613
- KEGG:D01213
- PMID:12742979
- PMID:16211205
- PMID:33078835
- PMID:34070416
- PMID:34386666
- PMID:34476570
- PMID:34514204
- PMID:34526469
- PMID:34554640
- Wikipedia:Tolvaptan
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
-
- inverse has_functional_parent
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Phenotype
Phenotype resulting from tolvaptan
Phenotype where environments contain tolvaptan
Phenotype modified by environments containing tolvaptan
Human Disease / Model Data
Citations