betaxolol

Term ID

CHEBI:3082

Synonyms

• 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol
• 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
• 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
• betaxolol
• betaxololum

Definition

A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.

References

• Beilstein:1991268
• CAS:63659-18-7
• DrugBank:DB00195
• Drug_Central:356
• HMDB:HMDB0014341
• KEGG:C06849
• KEGG:D07526
• LINCS:LSM-1255
• PMID:10891117
• PMID:1361581
• PMID:14971904
• PMID:15993593
• PMID:1865331
• PMID:2569884
• Patent:DE2649605
• Patent:US4252984
• Reaxys:1991268
• Wikipedia:Betaxolol

Ontology

ChEBI  ( EBI )

Resources

CTD