intercalator

Term ID

CHEBI:24853

Synonyms

agente intercalante
intercalating agent
intercalating agents
intercalating ligands
intercalators

Definition

A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: mutagen

mutagen Show first 5 Terms
inverse has_role: 3,6-diamino-10-methylacridinium chloride 3,6-diamino-10-methylacridinium chloride.HCl 3,6-diaminoacridine 3,6-diaminoacridine dihydrochloride 3,6-diaminoacridine monohydrochloride ... Show All 18 Terms

3,6-diamino-10-methylacridinium chloride 3,6-diamino-10-methylacridinium chloride.HCl 3,6-diaminoacridine 3,6-diaminoacridine dihydrochloride 3,6-diaminoacridine monohydrochloride acriflavinium chloride acriflavinium monochloride benzo[a]pyrene diol epoxide I ethidium ethidium bromide ethidium homodimer ICR-170 mitomycin nogalamycin propidium quinacrine mustard dihydrochloride saintopin steffimycin D Show first 5 Terms

Phenotype

Phenotype resulting from intercalator

Phenotype where environments contain intercalator

Phenotype modified by environments containing intercalator

Human Disease / Model Data

Citations