cinchocaine

Term ID

CHEBI:247956

Synonyms

• 2-butoxy-N-(2-(diethylamino)ethyl)cinchoninamide
• 2-butoxy-N-(alpha-diethylaminoethyl)cinchoninamide
• 2-butoxy-N-(beta-diethylaminoethyl)cinchoninamide
• 2-butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide
• 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
• 2-Butoxy-quinoline-4-carboxylic acid (2-diethylamino-ethyl)-amide
• 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide
• 2-N-butoxy-N-(2-diethylaminoethyl)cinchoninamide
• alpha-butyloxycinchonic acid-gamma-diethylethylenediamine
• alpha-butyloxycinchoninic acid diethylethylenediamide
• cinchocaine
• cinchocainum
• cincocainio
• Dibucaine
• dibucaine base
• N-(2-(diethylamino)ethyl)-2-butoxycinchoninamide

Definition

A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.

References

• Beilstein:275489
• CAS:85-79-0
• DrugBank:DB00527
• Drug_Central:859
• HMDB:HMDB0014668
• KEGG:C07879
• KEGG:D00733
• LINCS:LSM-6018
• PMID:23953476
• PMID:2873227
• Patent:US1825623
• Reaxys:275489
• Wikipedia:Dibucaine

Ontology

ChEBI  ( EBI )

Resources

CTD