BAY 73-6691

Term ID

CHEBI:231440

Synonyms

(R)-BAY 73-6691
(R)-BAY-73-6691
1-(2-chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one
1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
BAY 736691
BAY-73-6691
BAY736691

Definition

A member of the class of pyrazolopyrimidines that is 4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine substituted by 2-chlorophenyl, oxo, and (2R)-3,3,3-trifluoro-2-methylpropyl groups at positions 1, 4 and 6, respectively. It is a potent and selective inhibitor of phosphodiesterase 9 (PDE9), currently in pre-clinical development for the treatment of Alzheimer's disease.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: monochlorobenzenes organofluorine compound pyrazolopyrimidine

monochlorobenzenes organofluorine compound pyrazolopyrimidine Show first 5 Terms
has_role: apoptosis inducer EC 3.1.4.* (phosphoric diester hydrolase) inhibitor neuroprotective agent nootropic agent

apoptosis inducer EC 3.1.4.* (phosphoric diester hydrolase) inhibitor neuroprotective agent nootropic agent Show first 5 Terms

Phenotype

Phenotype resulting from BAY 73-6691

Phenotype where environments contain BAY 73-6691

Phenotype modified by environments containing BAY 73-6691

Human Disease / Model Data

Citations