Search Ontology:
ChEBI
pacritinib
- Term ID
- CHEBI:231350
- Synonyms
-
- (16E)-11-[2-(1-pyrrolidinyl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene
- (16E)-11-[2-(pyrrolidin-1-yl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene
- pacritinib
- pacritinibum
- SB 1518
- SB-1518
- SB1518
- Definition
- An azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis.
- References
-
- CAS:937272-79-2
- DrugBank:DB11697
- KEGG:D11768
- PDBeChem:6T3
- PMID:21604762
- PMID:25170285
- PMID:27598824
- PMID:29191878
- PMID:34551507
- PMID:35489775
- PMID:35567653
- PMID:35622972
- PMID:35877951
- PMID:35983661
- PMID:35993369
- PMID:36467816
- PMID:36469321
- PMID:36601980
- PMID:36651066
- PMID:36697489
- PMID:36822800
- PMID:36861402
- PMID:36922391
- PMID:36959157
- PMID:37203407
- PMID:37427653
- PMID:37552106
- PMID:37916436
- PMID:38164985
- PMID:38201581
- PMID:38295318
- PMID:38374336
- PMID:38562076
- PMID:38646919
- Wikipedia:Pacritinib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from pacritinib
Phenotype where environments contain pacritinib
Phenotype modified by environments containing pacritinib
Human Disease / Model Data
Citations