rezafungin

Term ID

CHEBI:229680

Synonyms

• 2-{[(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-({[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl}amino)tetraco
• biafungin
• CD-101
• CD101
• rezafungin cation
• rezafungin ion
• SP 3025
• SP-3025

Definition

A member of the family of echinocandins that inhibits 1,3-β-D-glucan synthase. It is developed by Cidara Therapeutics and approved for the treatment of candidaemia and invasive candidiasis in patients aged ≥ 18 years who have limited or no alternative treatment options.

References

• cas:1396640-59-7
• drugbank:DB16310
• kegg.drug:D11197
• pmc:PMC10266148
• pmc:PMC10266150
• pmc:PMC10266181
• pmc:PMC10677430
• pmc:PMC10678068
• pmc:PMC10761250
• pmc:PMC8643917
• pmc:PMC9752930
• pmc:PMC9848852
• pubmed:35249367
• pubmed:35439347
• pubmed:35778886
• pubmed:36191677
• pubmed:36442483
• pubmed:36442484
• pubmed:36855391
• pubmed:36879499
• pubmed:37154682
• pubmed:37212966
• pubmed:37247108
• pubmed:37247362
• pubmed:37342199
• pubmed:37367585
• pubmed:37470902
• pubmed:37494128
• pubmed:38008098
• pubmed:38008099
• pubmed:38014945
• pubmed:38161189
• pubmed:38461942
• pubmed:38476770
• pubmed:38497379
• pubmed:38502709
• pubmed:38526046
• wikipedia.en:Rezafungin

Ontology

ChEBI  ( EBI )