Search Ontology:
ChEBI
omaveloxolone
- Term ID
- CHEBI:229661
- Synonyms
-
- N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide
- N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-hexadecahydropicen-4a(2H)-yl]-2,2-difluoropropanamide
- omaveloxolona
- omaveloxolone
- omaveloxolonum
- RTA 408
- RTA-408
- RTA408
- Skyclarys
- Definition
- A semi-synthetic triterpenoid drug. It is an Nrf2 activator that is approved for the treatment of Friedreich's ataxia in adults and adolescents aged 16 years and older.
- References
-
- CAS:1474034-05-3
- DrugBank:DB12513
- KEGG:D10964
- PMID:28919776
- PMID:29476889
- PMID:29925185
- PMID:31185608
- PMID:31256292
- PMID:31487581
- PMID:33017422
- PMID:33295701
- PMID:34573098
- PMID:34709651
- PMID:35285087
- PMID:36032663
- PMID:36444905
- PMID:36708320
- PMID:37077825
- PMID:37094050
- PMID:37137161
- PMID:37142519
- PMID:37155124
- PMID:37219716
- PMID:37352984
- PMID:37691319
- PMID:37773082
- PMID:37795909
- PMID:37951537
- PMID:38047307
- PMID:38145457
- PMID:38269532
- PMID:38272714
- Wikipedia:Omaveloxolone
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_parent_hydride
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from omaveloxolone
Phenotype where environments contain omaveloxolone
Phenotype modified by environments containing omaveloxolone
Human Disease / Model Data
Citations