Search Ontology:
ChEBI
lotilaner
- Term ID
- CHEBI:229657
- Synonyms
-
- 3-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophene-2-carboxamide
- 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-2-thiophenecarboxamide
- Credelio
- lotilaner
- lotilanerum
- TP 03
- TP-03
- TP03
- Xdemvy
- Definition
- A member of the class of isoxazoles that is 4,5-dihydro-1,2-oxazole substituted by 4-methyl-5-({2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}carbamoyl)thiophen-2-yl, trifluoromethyl, and 3,4,5-trichlorophenyl groups at positions 3, 5 and 5, respectively (the 5S-stereoisomer). It is a gamma-aminobutyric acid (GABA)-gated chloride channel inhibitor selective for mites, approved for the treatment of Demodex blepharitis.
- References
-
- CAS:1369852-71-0
- DrugBank:DB17992
- KEGG:D11212
- PMID:29089066
- PMID:30001727
- PMID:30001745
- PMID:30071885
- PMID:31937370
- PMID:32904661
- PMID:33648556
- PMID:33673848
- PMID:34001200
- PMID:34001223
- PMID:34001224
- PMID:34044853
- PMID:34044864
- PMID:34088338
- PMID:34120646
- PMID:34311929
- PMID:34332895
- PMID:34603770
- PMID:35062996
- PMID:35965392
- PMID:36879347
- PMID:37285925
- PMID:37748769
- PMID:37843754
- PMID:37906372
- PMID:38301215
- PMID:38334465
- Pesticides:lotilaner
- Wikipedia:Lotilaner
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from lotilaner
Phenotype where environments contain lotilaner
Phenotype modified by environments containing lotilaner
Human Disease / Model Data
Citations