Search Ontology:
ChEBI
repotrectinib
- Term ID
- CHEBI:229220
- Synonyms
-
- Augtyro
- repotrectinib
- repotrectinibum
- TPX 0005
- TPX-0005
- TPX0005
- Definition
- An azamacrocycle with formula C18H18FN5O2. It is a tyrosine kinase inhibitor (highly potent against ROS1, TRKA-C, and ALK) used for the treatment of locally advanced or metastatic ROS1-positive non-small cell lung cancer.
- References
-
- CAS:1802220-02-5
- DrugBank:DB16826
- KEGG:D11454
- PDBeChem:7GI
- PMID:30093503
- PMID:30188734
- PMID:31852910
- PMID:32269053
- PMID:32278292
- PMID:34253025
- PMID:34482287
- PMID:34625502
- PMID:34834176
- PMID:35231576
- PMID:35334340
- PMID:35363931
- PMID:36201110
- PMID:37262390
- PMID:37909502
- PMID:37973688
- PMID:38047274
- PMID:38113652
- PMID:38144536
- PMID:38197815
- Wikipedia:Repotrectinib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from repotrectinib
Phenotype where environments contain repotrectinib
Phenotype modified by environments containing repotrectinib
Human Disease / Model Data
Citations