pirtobrutinib

Term ID

CHEBI:229212

Synonyms

• 5-amino-3-{4-[(5-fluoro-2-methoxybenzamido)methyl]phenyl}-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-pyrazole-4-carboxamide
• Jaypirca
• LOXO 305
• LOXO-305
• LY 3527727
• LY-3527727
• LY3527727
• pirtobrutinib
• pirtobrutinibum
• RXC-005
• RXC005

Definition

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-fluoro-2-methoxybenzoic acid with the amino group of 5-amino-3-[4-(aminomethyl)phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-pyrazole-4-carboxamide. It is a BTK inhibitor used for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.

References

• CAS:2101700-15-4
• Chemspider:114875989
• DrugBank:DB17472
• KEGG:D12050
• PDBeChem:Y7W
• PMCID:PMC10428413
• PMCID:PMC10429556
• PMCID:PMC10430907
• PMCID:PMC10431003
• PMCID:PMC10431162
• PMID:35196427
• PMID:35389384
• PMID:35747462
• PMID:35901282
• PMID:36287227
• PMID:36475521
• PMID:36519322
• PMID:36780414
• PMID:36796019
• PMID:36877244
• PMID:36960657
• PMID:37004673
• PMID:37156004
• PMID:37174062
• PMID:37192437
• PMID:37407001
• PMID:37509309
• PMID:37530617
• PMID:37624619
• PMID:37658026
• PMID:37818564
• PMID:38031799
• PMID:38043933
• Wikipedia:Pirtobrutinib

Ontology

ChEBI  ( EBI )