Search Ontology:
ChEBI

LY 379268

Term ID
CHEBI:192545
Synonyms
  • (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
  • LY-379,268
  • LY-379268
  • LY379268
Definition
An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from LY 379268
Phenotype where environments contain LY 379268
Phenotype modified by environments containing LY 379268
Human Disease / Model Data
Citations
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