PPDA

Term ID

CHEBI:189866

Synonyms

• (2S*,3R*)-1-(phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid
• cis-1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid
• cis-PPDA
• rac-(2R,3S)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid

Definition

A racemate comprising equimolar amounts of (2R,3S)- and (2S,3R)-PPDA. It is a subtype-selective NMDA receptor antagonist that preferentially binds to GluN2C/GluN2D (formally NR2C/NR2D) containing receptors.

References

• cas:684283-16-7
• pubmed:14718249
• pubmed:15743930
• pubmed:19684252
• pubmed:20936660
• pubmed:21497673
• pubmed:21651766
• pubmed:22950043
• pubmed:29531223
• pubmed:31969570
• pubmed:35057644

Ontology

ChEBI  ( EBI )