Search Ontology:
ChEBI

2,8-dihydroxyadenine

Term ID
CHEBI:183641
Synonyms
  • 2,8-DHA
  • 6-amino-2,8-dihydroxypurine
  • 6-amino-9H-purine-2,8-diol
  • 6-amino-purine-2,8-diol
Definition
A member of the class of 6-aminopurines that is adenine bearing two hydroxy substituents at positions 2 and 8. It is a highly insoluble metabolite of adenine that causes radiolucent urolithiasis. It is produced by individuals who suffer from adenine phosphoribosyltransferase (APRT) deficiency, a rare autosomal recessive error of purine metabolism.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse is_tautomer_of
is_tautomer_of
Phenotype
Phenotype resulting from 2,8-dihydroxyadenine
Phenotype where environments contain 2,8-dihydroxyadenine
Phenotype modified by environments containing 2,8-dihydroxyadenine
Human Disease / Model Data
Citations
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