amperozide

Term ID

CHEBI:180480

Synonyms

4-(4,4-bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide
4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide
amperozida
amperozide
amperozidum

Definition

A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: diarylmethane monofluorobenzenes N-alkylpiperazine secondary carboxamide ureas

diarylmethane monofluorobenzenes N-alkylpiperazine secondary carboxamide ureas Show first 5 Terms
has_role: anxiolytic drug dopamine uptake inhibitor geroprotector second generation antipsychotic serotonergic antagonist

anxiolytic drug dopamine uptake inhibitor geroprotector second generation antipsychotic serotonergic antagonist Show first 5 Terms
inverse is_conjugate_acid_of: amperozide(1+)

amperozide(1+) Show first 5 Terms
is_conjugate_base_of: amperozide(1+)

amperozide(1+) Show first 5 Terms

Phenotype

Phenotype resulting from amperozide

Phenotype where environments contain amperozide

Phenotype modified by environments containing amperozide

Human Disease / Model Data

Citations