N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}methanesulfonamide

Term ID

CHEBI:177875

Synonyms

N-[2-(4-benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-yl]-methanesulfonamide
N-{2-[(4-benzylpiperidin-1-yl)methyl]-1H-benzimidazol-6-yl}methanesulfonamide
N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}methanesulphonamide
N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}propane-2-sulfonamide
XK1

Definition

A member of the class of benzimidazoles that is 1H-benzimidazole substituted by (4-benzylpiperidin-1-yl)methyl and (methylsulfonyl)amino groups at positions 2 and 6, respectively. It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzenes benzimidazoles piperidines sulfonamide tertiary amino compound

benzenes benzimidazoles piperidines sulfonamide tertiary amino compound Show first 5 Terms
has_role: neuroprotective agent NMDA receptor antagonist

neuroprotective agent NMDA receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}methanesulfonamide

Phenotype where environments contain N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}methanesulfonamide

Phenotype modified by environments containing N-{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl}methanesulfonamide

Human Disease / Model Data

Citations