ceramide

Term ID

CHEBI:17761

Synonyms

a ceramide
Cer
Ceramide
ceramides
N-acylated sphingoid

Definition

Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H.

References

KEGG:C00195
LIPID_MAPS_class:LMSP02
PMID:7542630
Wikipedia:Ceramide

Ontology

ChEBI ( EBI )

Relationships

is a type of: carboxamide sphingolipid

carboxamide sphingolipid Show first 5 Terms
has subtype: (2R,3E)-N-((2S,3R,4E,8E,10E)-1,3-dihydroxyoctadeca-4,8,10-trien-2-yl)-2-hydroxy-6-methyloctadec-3-enimidic acid (2S,2′R,3R,4E,8E)-N-2′-hydroxyhexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,2′R,3R,4E,8E)-N-2′-hydroxypentadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,2′R,3R,4E,8E)-N-2′-hydroxytetradecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,3R,4E,8E)-N-hexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol ... Show All 74 Terms

(2R,3E)-N-((2S,3R,4E,8E,10E)-1,3-dihydroxyoctadeca-4,8,10-trien-2-yl)-2-hydroxy-6-methyloctadec-3-enimidic acid (2S,2′R,3R,4E,8E)-N-2′-hydroxyhexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,2′R,3R,4E,8E)-N-2′-hydroxypentadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,2′R,3R,4E,8E)-N-2′-hydroxytetradecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,3R,4E,8E)-N-hexadecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (2S,3R,4E,8E,9′Z,12′Z)-N-9′,12′-octadecadienoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol (E,2R)-N-[(2S,3R,4E,8E)-1,3-dihydroxy-9-methyloctadeca-4,8-dien-2-yl]-2-hydroxyoctadec-3-enamide 1-O-acyl-N-acylsphingosine 1-O-acylceramide Asperamide A Cer(d16:1(4E)/20:0(2OH)) Cer(d16:1/18:0) Cer(d16:2(4E,6E)/22:1(13Z)(2OH)) Cer(d16:2(4E,6E)/24:0(2OH)) Cer(d18:0/17:0) Cer(d18:0/18:1(11Z)) Cer(d18:0/23:0) Cer(d18:0/h24:0) Cer(d18:1(8Z)/19:0) Cer(d18:1/18:1(11Z)) Cer(d18:2/18:1) ceramide 1-phosphate ceramide 1-phosphonate cerebroside ganglioside glycosylceramide N-(1,3-dihydroxyoctadec-4-en-2-yl)acetamide N-(2-hydroxy-tetracosanoyl)-hexadecasphing-4-enine N-(2-hydroxyacyl)sphingoid N-(2-hydroxyhenicosanoyl)-4,8-sphingadienine N-(2-hydroxytridecanoyl)-phytosphingosine N-[(2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]pentacosanimidic acid N-[(2S,3S,4R,8E)-1,3,4-Trihydroxy-8-octadecen-2-yl]icosanamide N-[(4E,8E)-1,3-dihydroxyoctadec4,8-dien-2-yl]hexadecanamide N-[(4E,8E)-1,3-dihydroxyoctadeca-4,8-dien-2-yl]hexadecanamide N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-ceramide N-[omega-(acylyloxy)]acylsphin-4-enine N-acyl-(4E,8E)-9-methylsphinga-4,8-dienine N-acyl-(4E,8E)-sphinga-4,8-dienine N-acyl-(4E,8E,10E)-sphinga-4,8,10-trienine N-acyl-(4E,8Z)-sphinga-4,8-dienine N-acyl-(4E,14Z)-sphingadienine N-acyl-1-deoxy-4-hydroxysphinganine N-acyl-1-deoxysphinganine N-acyl-1-deoxysphingosine N-acyl-15-methylhexadecasphing-4-enine N-acylheptadecasphingosine N-acylhexadecasphingosine N-acylsphingoid N-acyltetradecasphing-4-enine N-docosanoyl-(4E,14Z)-sphinga-4,14-dienine N-docosanoyl-14-methylhexadecasphingosine N-henicosanoyl-14-methylhexadecasphingosine N-heptadecanoyl-14-methylhexadecasphingosine N-hexacosanoyl-14-methylhexadecasphinganine N-hexacosanoyl-14-methylhexadecasphingosine N-hexadecanoyl-14-methylhexadecasphingosine N-Octanoyl-D-sphingosine N-omega-linoleoyloxy-fatty acyl-sphingoid base N-palmitoyl-d-sphingosine N-pentacosanoyl-14-methylhexadecasphingosine N-tetracosanoyl-14-methylhexadecasphingosine N-tetracosenoyl-C17-sphingosine N-tricosanoyl-(4E,14Z)-sphinga-4,14-dienine N-tricosanoyl-14-methylhexadecasphingosine N-tricosenoyl-14-methylhexadecasphingosine oligoglycosylceramide omega-hydroxy-ultra-long chain fatty acylceramide omega-linoleoyloxy-O-ultra-long chain acylceramide oxidized ceramide Pecipamide phosphocerebroside phytoceramides Show first 5 Terms

Phenotype

Phenotype resulting from ceramide

Phenotype where environments contain ceramide

Phenotype modified by environments containing ceramide

Human Disease / Model Data

Citations