Search Ontology:
ChEBI

plinabulin

Term ID
CHEBI:177413
Synonyms
  • (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione
  • BPI 2358
  • BPI-2358
  • NPI 2358
  • NPI-2358
  • NPI2358
  • plinabulin
  • plinabulina
  • plinabuline
  • plinabulinum
Definition
A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from plinabulin
Phenotype where environments contain plinabulin
Phenotype modified by environments containing plinabulin
Human Disease / Model Data
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.