komodoquinone A

Term ID

CHEBI:167003

Synonyms

(+)-komodoquinone A
(8S,10S)-6,8,10,11-tetrahydroxy-8-methyl-5,12-dioxo-5,7,8,9,10,12-hexahydrotetracen-1-yl 3,6-dideoxy-3-(dimethylamino)-alpha-L-galactopyranoside

Definition

An anthracycline that is komodoquinone B in which the hydroxy group at position 1 is replaced by a 3,6-dideoxy-3-(dimethylamino)-alpha-L-galactopyranoside group. First isolated from the marine bacterium Streptomyces sp. KS3, it induces neuronal cell differentiation in the neuroblastoma cell line.

References

CAS:630094-57-4
KNApSAcK:C00031956
PMID:14575440
PMID:14646317
PMID:30995392
Patent:JP2005080616

Ontology

ChEBI ( EBI )

Relationships

is a type of: aminoglycoside anthracycline diketone tertiary alcohol tertiary amino compound ... Show All 6 Terms

aminoglycoside anthracycline diketone tertiary alcohol tertiary amino compound tetracenequinones Show first 5 Terms
has_functional_parent: komodoquinone B

komodoquinone B Show first 5 Terms
has_role: bacterial metabolite marine metabolite

bacterial metabolite marine metabolite Show first 5 Terms

Phenotype

Phenotype resulting from komodoquinone A

Phenotype where environments contain komodoquinone A

Phenotype modified by environments containing komodoquinone A

Human Disease / Model Data

Citations