leukotriene B4

Term ID

CHEBI:15647

Synonyms

• (5S,12R,6Z,8E,10E,14Z)-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid
• (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyeicosa-6,8,10,14-tetraenoic acid
• (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
• (S-(R*,S*-(E,Z,E,Z)))-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid
• 5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoic acid
• 5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-icosatetraenoic acid
• 5,12-Dihete
• 5,12-Hete
• 5S,12R-diHETE
• 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
• Leukotriene B4
• LTB4

Definition

A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. It is a lipid mediator of inflammation that is generated from arachidonic acid via the 5-lipoxygenase pathway.

References

• CAS:71160-24-2
• Chemspider:4444132
• DrugBank:DB12961
• HMDB:HMDB0001085
• KEGG:C02165
• KNApSAcK:C00053425
• LIPID_MAPS_instance:LMFA03020001
• PDBeChem:LTB
• PMID:10087000
• PMID:10391868
• PMID:10695938
• PMID:11166796
• PMID:11254552
• PMID:12709426
• PMID:12742837
• PMID:12947016
• PMID:1327049
• PMID:1333134
• PMID:1335872
• PMID:1338371
• PMID:15016629
• PMID:15515787
• PMID:16567388
• PMID:1661709
• PMID:17481557
• PMID:17548641
• PMID:17623009
• PMID:1847289
• PMID:20400503
• PMID:20529300
• PMID:20671299
• PMID:23625922
• PMID:32439596
• PMID:32960415
• PMID:33292560
• PMID:33612149
• PMID:6271967
• PMID:7924852
• PMID:8243477
• PMID:8382716
• PMID:8397308
• PMID:9209678
• PMID:9516893
• PMID:9606840
• Reaxys:4235309
• Wikipedia:Leukotriene_B4

Ontology

ChEBI  ( EBI )

Resources

CTD