oviedomycin

Term ID

CHEBI:156291

Synonyms

• 2,6,8-trihydroxy-3-methyl-1,4,7,12-tetrahydrotetraphene-1,4,7,12-tetrone
• 2,6,8-trihydroxy-3-methyl-benz[a]anthracene-1,4,7,12-tetrone
• 2,6,8-trihydroxy-3-methyltetraphene-1,4,7,12-tetrone
• 3-methyl-2,6,8-trihydroxybenzo[a]anthracene-1,4,7,12-tetrone

Definition

A member of the class of tetraphenes that is 1,4,7,12-tetrahydrotetraphene substituted by oxo groups at positions 1, 4, 7, and 12, by hydroxy groups at positions 2, 6 and 8, and by a methyl group at position 3. It is a natural product found in Streptomyces antibioticus ATCC 11891 which exhibits cytotoxicity against A549 human lung cancer cells, HepG2 liver cancer cells, and MCF-7 breast cancer cells.

References

• CAS:439127-45-4
• KNApSAcK:C00046255
• MetaCyc:CPD-12942
• PMID:12027768
• PMID:15368568
• PMID:18988223
• PMID:25303210
• PMID:28972184

Ontology

ChEBI  ( EBI )