ascofuranone

Term ID

CHEBI:156148

Synonyms

(-)-ascofuranone
(S)-ascofuranone
(S-(E,E))-3-chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)-2,6-octadienyl)-benzaldehyde
3-chloro-5-{(2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl}-4,6-dihydroxy-2-methylbenzaldehyde
ascofuranon

Definition

A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by the soil fungus, Acremonium sclerotigenum. It is a promising drug candidate against the tropical disease, African trypanosomiasis.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: dihydroxybenzaldehyde meroterpenoid monochlorobenzenes olefinic compound resorcinols ... Show All 7 Terms

dihydroxybenzaldehyde meroterpenoid monochlorobenzenes olefinic compound resorcinols sesquiterpenoid tetrahydrofuranone Show first 5 Terms
has_role: angiogenesis inhibitor antilipemic drug antineoplastic agent antiprotozoal drug fungal metabolite

angiogenesis inhibitor antilipemic drug antineoplastic agent antiprotozoal drug fungal metabolite Show first 5 Terms
inverse is_conjugate_base_of: ascofuranone(1-)

ascofuranone(1-) Show first 5 Terms
is_conjugate_acid_of: ascofuranone(1-)

ascofuranone(1-) Show first 5 Terms

Phenotype

Phenotype resulting from ascofuranone

Phenotype where environments contain ascofuranone

Phenotype modified by environments containing ascofuranone

Human Disease / Model Data

Citations