TDZD-8

Term ID

CHEBI:147411

Synonyms

4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
NP 01139
thiadiazolidinone-8

Definition

A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzenes thiadiazolidine

benzenes thiadiazolidine Show first 5 Terms
has_role: anti-inflammatory agent antineoplastic agent apoptosis inducer EC 2.7.11.26 (tau-protein kinase) inhibitor neuroprotective agent

anti-inflammatory agent antineoplastic agent apoptosis inducer EC 2.7.11.26 (tau-protein kinase) inhibitor neuroprotective agent Show first 5 Terms

Phenotype

Phenotype resulting from TDZD-8

Phenotype where environments contain TDZD-8

Phenotype modified by environments containing TDZD-8

Human Disease / Model Data

Citations