estetrol

Term ID

CHEBI:142773

Synonyms

• (15alpha,16alpha,17beta)-estra-1(10),2,4-triene-3,15,16,17-tetrol
• (8R,9S,13S,14S,15R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,15,16,17-tetrol
• 15alpha-hydroxyestriol
• 3,15alpha,16alpha,17beta-tetrahydroxyestra-1,3,5(10)-triene
• Donesta
• estetrol
• estetrolum
• estra-1(10),2,4-triene-3,15alpha,16alpha,17beta-tetrol
• estra-1,3,5(10)-triene-3,15alpha,16alpha,17beta-tetrol
• oestetrol

Definition

A 3-hydroxy steroid that is 17β-estradiol which has been substituted at the 15α and 16α positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver.

References

• cas:15183-37-6
• drugbank:DB12235
• patent:EP2383279
• pdb-ccd:4OH
• pubmed:1222727
• pubmed:18462934
• pubmed:18464016
• pubmed:18464023
• pubmed:19167495
• pubmed:23992378
• pubmed:25079370
• pubmed:25961355
• pubmed:26212489
• pubmed:27799463
• pubmed:28267365
• pubmed:28364860
• pubmed:28371720
• pubmed:28641030
• pubmed:28827141
• pubmed:29928930
• pubmed:29931320
• pubmed:30308312
• pubmed:4003113
• pubmed:545977
• wikipedia.en:Estetrol

Ontology

ChEBI  ( EBI )

Resources

CTD