vericiguat

Term ID

CHEBI:142432

Synonyms

• BAY-1021189
• BAY1021189
• methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
• methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate
• MK-1242
• vericiguat
• vericiguatum

Definition

A pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substituted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure.

References

• CAS:1350653-20-1
• KEGG:D11051
• PMCID:PMC4565100
• PMID:24092345
• PMID:25056511
• PMID:25737289
• PMID:26547357
• PMID:28369340
• PMID:28557445
• PMID:29032136
• Patent:US2012022084
• Reaxys:22098890

Ontology

ChEBI  ( EBI )