AZD1979

Term ID

CHEBI:139154

Synonyms

[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]{3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy]azetidin-1-yl}methanone
AZD 1979
AZD-1979

Definition

A carboxamide resulting from the formal condensation of the carboxy group of 5-(p-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylic acid with the amino group of 3-phenoxyazetidine and in which the phenoxy group has been substituted at the para- position by a 2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl group. It is a melanin concentrating hormone receptor 1 (MCHr1) antagonist.

References

CAS:1254035-84-1
MetaCyc:CPD-20318
PMID:26741166
PMID:27256986
PMID:27400775
PMID:28556607
Patent:WO2010125390
Reaxys:20834832

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether azaspiro compound carboxamide N-acylazetidine oxadiazole ... Show All 7 Terms

aromatic ether azaspiro compound carboxamide N-acylazetidine oxadiazole oxaspiro compound oxetanes Show first 5 Terms
has_role: melanin-concentrating hormone receptor antagonist

melanin-concentrating hormone receptor antagonist Show first 5 Terms
inverse has_functional_parent: AZD1979 oxetane hydrolysis product

AZD1979 oxetane hydrolysis product Show first 5 Terms
inverse is_conjugate_acid_of: AZD1979(1+)

AZD1979(1+) Show first 5 Terms
is_conjugate_base_of: AZD1979(1+)

AZD1979(1+) Show first 5 Terms

Phenotype

Phenotype resulting from AZD1979

Phenotype where environments contain AZD1979

Phenotype modified by environments containing AZD1979

Human Disease / Model Data

Citations