lifitegrast

Term ID

CHEBI:133023

Synonyms

lifitegrast
N-[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbonyl]-3-(methanesulfonyl)-L-phenylalanine
SAR 1118
SAR-1118
SAR1118
Xiidra

Definition

An N-acyl-L-alpha-amino acid obtained by formal condensation of the carboxy group of N-[2-(1-benzofuran-6-carbonyl)]-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid with the amino group of 3-(methanesulfonyl)-L-phenylalanine. Used for treatment of keratoconjunctivitis sicca (dry eye syndrome).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 1-benzofurans isoquinolines L-phenylalanine derivative N-acyl-L-alpha-amino acid sulfone

1-benzofurans isoquinolines L-phenylalanine derivative N-acyl-L-alpha-amino acid sulfone Show first 5 Terms
has_role: anti-inflammatory drug lymphocyte function-associated antigen-1 antagonist

anti-inflammatory drug lymphocyte function-associated antigen-1 antagonist Show first 5 Terms

Phenotype

Phenotype resulting from lifitegrast

Phenotype where environments contain lifitegrast

Phenotype modified by environments containing lifitegrast

Human Disease / Model Data

Citations