sumatriptan

Term ID

CHEBI:10650

Synonyms

• (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
• 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
• 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide
• 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide
• 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide
• Imigran
• Imitrex
• Sumatran
• sumatriptan
• sumatriptanum
• Sumax

Definition

A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

References

• Beilstein:5346011
• CAS:103628-46-2
• DrugBank:DB00669
• Drug_Central:2543
• HMDB:HMDB0005037
• KEGG:C07319
• KEGG:D00451
• LINCS:LSM-5618
• PMID:11045888
• PMID:11401410
• PMID:12172708
• PMID:12856385
• PMID:12917936
• PMID:15652399
• PMID:16120224
• PMID:16142613
• PMID:17557349
• PMID:18442019
• PMID:19619527
• PMID:19825906
• PMID:22106962
• PMID:22150557
• PMID:22272067
• PMID:22302025
• PMID:22336849
• PMID:22336867
• PMID:22336868
• PMID:22435741
• Reaxys:5346011
• Wikipedia:Sumatriptan

Ontology

ChEBI  ( EBI )

Resources

CTD