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ChEBI

N(2)-acetyl-N(6)-(1,4-dihydroxynonan-3-yl)-L-lysine

Term ID
CHEBI:102266
Synonyms
  • HNE-modified N-acetyl-L-lysine
  • N(2)-acetyl-N(6)-[1-(2-hydroxyethyl)-2-hydroxyheptyl]-L-lysine
  • N(2)-acetyl-N(6)-[2-hydroxy-1-(2-hydroxyethyl)heptyl]-L-lysine
  • N(alpha)-acetyl-N(epsilon)-(1,4-dihydroxynonan-3-yl)-L-lysine
  • N(alpha)-acetyl-N(epsilon)-[1-(2-hydroxyethyl)-2-hydroxyheptyl]-L-lysine
  • N(alpha)-acetyl-N(epsilon)-[2-hydroxy-1-(2-hydroxyethyl)heptyl]-L-lysine
Definition
An L-lysine derivative in which the alpha-amino nitrogen of the amino acid has entered into amide formation with acetic acid and the epsilon-amino nitrogen carries a 1,4-dihydroxynonan-3-yl substituent. It has been synthesised by reaction of (E)-4-hydroxynon-2-enal (HNE) with N(2)-acetyl-L-lysine, the epsilon amino group of lysine reacting with the double bond function of HNE via formation of a Michael adduct.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
Phenotype
Phenotype resulting from N(2)-acetyl-N(6)-(1,4-dihydroxynonan-3-yl)-L-lysine
Phenotype where environments contain N(2)-acetyl-N(6)-(1,4-dihydroxynonan-3-yl)-L-lysine
Phenotype modified by environments containing N(2)-acetyl-N(6)-(1,4-dihydroxynonan-3-yl)-L-lysine
Human Disease / Model Data
Citations