| OBO ID: GO:1990303 |
| Term Name: | UBR1-RAD6 ubiquitin ligase complex | Search Ontology: | |
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| Definition: | A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes. 19531475 | ||
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| Ontology: | GO: Cellular Component QuickGO AmiGO |
Show first 5 Terms
EXPRESSION
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PHENOTYPE
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