Term Name: |
neurofibrillary tangle |
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Search Ontology:
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Synonyms: |
- flame-shaped neurofibrillary tangle
- star-shaped neurofibrillary tangle
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Definition: |
Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
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References: |
- NIF_Subcellular:nlx_subcell_20090201
- NIF_Subcellular:nlx_subcell_20090202
- NIF_Subcellular:sao2409833926
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Ontology: |
GO: Cellular Component
QuickGO
AmiGO
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