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catalytic step 2 spliceosome
mammalian spliceosomal complex C
mammalian spliceosomal complex C1
yeast spliceosomal complex A2-2
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.