| OBO ID: GO:0045240 |
| Term Name: | alpha-ketoacid dehydrogenase complex | Search Ontology: | |
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| Definition: | A multi-enzyme complex that catalyzes the oxidative decarboxylation of an alpha-ketoacid - pyruvate, a branched-chain alpha-ketoacid or alpha-ketoglutarate (also known as 2-oxoglutarate). The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: a dihydrolipoyl transacylase (E2) forms the core of the complex, with an alpha-ketoacid dehydrogenase (E1) and a dihydrolipoamide dehydrogenase (E3) attached through non-covalent bonds. The E1 and E2 components are specific to different alpha-ketoacid dehydrogenase complexes, whereas the E3 component is the same. Additional proteins may also be present. 10745006 | ||
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| Ontology: | GO: Cellular Component QuickGO AmiGO |
Show first 5 Terms
EXPRESSION
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PHENOTYPE
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