OBO ID: GO:0031264
Term Name: death-inducing signaling complex Search Ontology:
Synonyms:
  • death receptor-induced signaling complex
  • death receptor-induced signalling complex
  • death-inducing signalling complex
  • DISC
  • DISC protein complex
Definition: A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10. (3)
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available