ZFIN GO: Biological Process: Notch signaling pathway

OBO ID: GO:0007219

Term Name:	Notch signaling pathway		Search Ontology:
Synonyms:	N signaling pathway N signalling pathway Notch receptor signaling pathway Notch receptor signalling pathway Notch signalling pathway Notch-receptor signaling pathway Notch-receptor signalling pathway
Definition:	The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
References:	Wikipedia:Notch_signaling_pathway
Ontology:	GO: Biological Process QuickGO AmiGO

Relationships

has parts:	Notch receptor processing, ligand-dependent positive regulation of transcription of Notch receptor target Notch receptor processing, ligand-dependent positive regulation of transcription of Notch receptor target Show first 5 Terms
is a type of:	cell surface receptor signaling pathway cell surface receptor signaling pathway Show first 5 Terms
has subtype:	Notch signaling involved in heart development Notch signaling pathway involved in arterial endothelial cell fate commitment Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Notch signaling pathway involved in forebrain neuroblast division Notch signaling pathway involved in forebrain neuron fate commitment ... Show All 9 Terms Notch signaling involved in heart development Notch signaling pathway involved in arterial endothelial cell fate commitment Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Notch signaling pathway involved in forebrain neuroblast division Notch signaling pathway involved in forebrain neuron fate commitment Notch signaling pathway involved in heart induction Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation Notch signaling pathway involved in somitogenesis Show first 5 Terms
negatively regulated by:	negative regulation of Notch signaling pathway negative regulation of Notch signaling pathway Show first 5 Terms
positively regulated by:	positive regulation of Notch signaling pathway positive regulation of Notch signaling pathway Show first 5 Terms
regulated by:	regulation of Notch signaling pathway regulation of Notch signaling pathway Show first 5 Terms

PHENOTYPE