| Term Name: |
second spliceosomal transesterification activity |
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Search Ontology:
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| Synonyms: |
- 3'-splice site cleavage, exon ligation
- lariat formation, 5'-splice site cleavage
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| Definition: |
Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
(2)
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| References: |
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| Ontology: |
GO: Molecular Function
QuickGO
AmiGO
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